Nitrous Oxide-Oxygen Inhalation Sedation in Paediatric Dental Patients: A Review


  • Jane W.H. Lim Department of Paediatric Dentistry, Hospital Tawau, Sabah, Malaysia
  • Sri Kavi Subramaniam Department of Paediatric Dentistry, Hospital Sultanah Aminah, Johor Bahru, Johor, Malaysia
  • Suriani Sukeri Department of Paediatric Dentistry, Hospital Tunku Azizah, Kuala Lumpur, Malaysia
  • Ganasalingam Sockalingam Department of Paediatric Dentistry, Hospital Tunku Azizah, Kuala Lumpur, Malaysia



Nitrous-Oxide, Sedation, Paediatric, Dental


Provision of sedation while delivering dental treatment to anxious paediatric patients aims in minimising their discomfort and psychological trauma, managing behaviour as well as controlling patient movements, using a technique with wide margin of safety. Nitrous oxide-oxygen inhalation sedation is one of the sedation methods commonly used to manage dental fear and anxiety. Its beneficial features include; potent anxiolytic effect, its sedative, analgesic as well as amnesic properties, titratability, rapid onset and recovery whilst carrying minimum risk. Modern dental inhalation sedation machines deliver gases in continuous flow mechanism, using nasal hood apparatus therefore allowing treatment to the oral cavity. The machine is equipped with various safety features to avoid adverse events during administration. Operators must be adequately trained and able to manage foreseeable complications. This paper aims to provide an overview on the appropriate practice of nitrous oxide-oxygen inhalation sedation, for paediatric dental patients. Careful case selection, comprehensive preparation by the sedation team, good documentation, the use of appropriate armamentarium, application of titration techniques along with good behaviour management are crucial in producing safe and effective treatment outcomes.


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How to Cite

Lim, J. W. ., Subramaniam, S. K. ., Sukeri, S., & Sockalingam, G. . (2022). Nitrous Oxide-Oxygen Inhalation Sedation in Paediatric Dental Patients: A Review. Malaysian Journal of Paediatrics and Child Health, 28(1), 91-100.



Review Article