CPG – Management of Transfusion Dependent Thalassaemia – Nov 2009

1. INTRODUCTION The thalassaemias are a heterogeneous group of genetic disorders with defective synthesis of one or more globin chains. In Malaysia, the most common types are the α and β thalassaemias. The β thalassaemias together with its heterozygous interaction with HbE disease constitute the bulk of the patients’ load. The most recent data from the Malaysian Thalassaemia Registry…

CPG – Management of Attention Deficit Hyperactivity Disorder in Children And Adolescents – Oct 2008

1. INTRODUCTION Attention Deficit Hyperactivity Disorder (ADHD) is one of the most frequently encountered childhood-onset neuro-behavioural disorders in primary care settings. It has defining features of inattention, over-activity and impulsivity. The core symptoms co-exist with other emotional, behavioural and learning disorders.1, 2 Often primary care physicians, paediatricians, psychiatrists, clinical psychologists and others are asked to evaluate and treat a…

CPG – Management of Immune Thrombocytopenic Purpura – August 2006

1. INTRODUCTION Immune thrombocytopenic purpura (ITP) affects both children and adults. It is an autoimmune disorder characterised by persistent thrombocytopenia (peripheral platelet count of less than 150 x109/L) due to autoantibody binding to platelet antigen(s) causing their premature destruction by the reticuloendothelial system, in particular the spleen. In childhood, the peak age is 2-4 years, girls and boys are…

CPG – Withholding and Withdrawing of Life Support in Children – Dec 2005

1. INTRODUCTION Technological advances in modern medicine have had a great impact on the care of critically ill patients, saving many children’s lives, but also leaving others with chronic diseases and disabilities. The increased ability to sustain life with intensive care may lead, unfortunately, sometimes only to prolonging suffering when treatment is unsuccessful, and prolonging the dying process, attached…